The Ultimate Active Immunostaining Device

Rapid Immunostaining with Unparalleled Uniformity

Fast, Easy, and Efficient

Fast: Label large, intact samples such as rodent organs an order of magnitude faster than with passive labeling (≤ 24 hours vs. weeks to months).

Easy: Turnkey operation – simply load the buffers and your sample & probes. Perform 2 distinct labeling experiments simultaneously thanks to SmartLabel’s dual chamber design.

Efficient: Uses a small amount of antibody (as little as ~3 µg) to label tissues the size of a whole mouse brain.

Reliable: Prevents tissue damage with Stochastic Electrotransport technology (Kim, PNAS, 2015). Our nanoporous membranes (patent-pending) eliminate tissue contamination and probe loss.

Complete and Uniform Labeling

• Achieves unparalleled uniformity of signal intensity from surface to core using LifeCanvas’s advanced eFLASH (Yun, bioRxiv, 2019) protocol

• Combines rapid, Stochastic Electrotransport-mediated (Kim, PNAS, 2015) infiltration of probes into tissue with the SWITCH technique (Murray, Cell, 2015) of controlling probe binding kinetics 

Cost Savings by Avoiding Target Saturation

• Prevents antibody depletion caused by excessive binding to superficial tissue sites and ensures the sample’s center is well-labeled.

Compatible with Many Cleared - Tissue Techniques

• SHIELD (Park, Nature Biotechnology, 2018)

• MAP (Ku, Nature Biotechnology, 2016)

• SWITCH (Murray, Cell, 2015)

þ Features

• Fast, Easy, and Efficient

• Complete and Uniform Labeling

• Cost Savings by Avoiding Target Saturation

• Compatible with Many Cleared-Tissue Techniques