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In-Vitro MEA2100-Beta-Screen-System Multi Channel Systems(MCS), Germany

Beta Cell Screening

Acute and chronic recordings of glucose-induced electrical activity in pancreatic beta cells

 

MEA-based simultaneous screening of islets of Langerhans

The MEA2100-Beta-Screen-System is an in vitro recording system optimized for diabetes research with beta cells in intact islets of Langerhans. Non-invasive in vitro MEA technology enables acute long-term recording of up to 40 islets simultaneously. Built-in suctions allows fixation and optimal positioning of the islets on the electrodes. The system consists of a 5-channel headstage with build-in perfusion, featuring a sampling rate of 50 kHz per channel at a 24 bit resolution. 

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The digitized data is transferred from the headstage to a signal collector unit for up to four headstages. The signal collector unit is connected to the interface board.


þ Features 

 

 Non-invasive method enables long-term in vitro diabetes research

 Simplified experimental handling with higher throughput than

conventional methods, ideal for both academic and industrial laboratories

 Easy and fast versus conventional, invasive methods such as patchclamp and recording with intracellular electrodes

 Intact islets now allow electrophysiological screening in drug development

 


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