Respirometry Head-out Plethysmographs (DSI Buxco®, USA)
Head-Out plethysmographs are used to study restrained, conscious subjects. It is the most cost-effective solution for measuring basic respiratory endpoints. It is a very reliable and simple method due to the direct measurement of air being displaced by the test subject’s expanding and contracting thorax. When using a head-out chamber, no other peripheral equipment is required such as temperature sensors, humidity sensors or bias air flow which significantly reduces the system cost.
The Head-Out plethysmography system is ideal for researchers interested longitudinal studies without the use of anesthesia. Chambers are also compatible with other data acquisition systems including DSI Ponemah, which allows for the addition of telemetry endpoints to be collected simultaneously. The rat chamber has been designed specifically for the demanding Safety Assessment environment.
Key Features:
- Supported Species: Mouse Pup, Mouse, Rat (3 sizes), Rabbit, NHP
- Continuously measures respiratory flow signals in conscious animal
- Chambers utilize easy to operate restraint systems and integrated pneumotach
- Up to 8 chambers can be measure simultaneously with one Buxco amplifier
- Multiple amplifiers can be simultaneously interfaced with one software license
- Low noise, 24 bit A/D amplifier design with USB interface to computer
Key Benefits:
- Patented Allay™ Restraint - secures the animal without compressing the thorax (Mouse & Rat)
- Patented Halcyon® pneumotach noise suppression design improves signal morphology*
- Species flexibility – software, amplifier and transducers support all Head-Out chamber designs
- FinePointe Software – integrated study design and subsequent automated reporting
- Solid State Flow Transducer – small, rugged, low drift, high fidelity transducer mounts directly to chamber
* Not included on all chamber designs
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