Tissue Clearing SmartBatch+ LifeCanvas, USA
New high-throughput system for rapid active tissue clearing and immunolabeling
SmartBatch+ combines active tissue clearing, leveraging our new Clear+ system, and active immunolabeling into one turn-key batch tissue processing device! Now you can clear and label up to 12 whole mouse brains in just one day.

An advance on our founder’s CLARITY method, Clear+ tissue clearing provides maximum optical transparency with no tissue expansion; eFLASH and patented SE technologies then uniformly label whole organs from surface to core.
þ Features
• Multi-functional: Switches between clearing and labeling modes simply by changing buffers.
• Fast, uniform labeling: Our system uses eFLASH technology(bioRxiv 2019), combining SWITCH (Cell 2015) with our patented stochastic electrotransport (SE, PNAS 2015) method to uniformly label intact tissue volumes.
• Cost-effective: SmartBatch+ uses just 4-20 μg of antibody per target to label a sample the size of a whole mouse brain, and requires <12 mins hands-on time per sample.
• High-throughput: Our device can actively clear or label up to 12 whole mouse brains, 2 whole rat brains, or comparably sized samples per batch.
• Ideal for light sheet imaging: Combined with SHIELD tissue preservation, SmartBatch+ protects fluorescent protein signal, antigenicity, and molecular & physical architecture through all tissue processing steps.
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